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How much CBD is too much?

by Green Machine on August 12, 2019

It's a question as old as CBD itself. 

How much is too much?

Well if you ask a doctor in the UK, they probably won't know. If you ask a doctor in the USA he might respond with a question like...

Depends on how much THC your taking and how that lines up with your prescription. 

However for us trapped in the middle of the legislative nightmare, the people on the ground selling these products day in, day out. 

our hands are tied. We cannot give medical advice. 

So with that in mind, we're only able to give factual information regarding well documented information. 

The WHO (World Health Organisation) states in their most recent critical analysis of CBD. 

https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf

"Toxicology
The potential toxic effects of CBD have been extensively reviewed [52] with a recent update of the literature. [53] In general, CBD has been found to have relatively low toxicity, although not all potential effects have been explored. The following are some of the relevant findings to date from in vitro and animal studies:
• CBD affects growth of tumoral cell lines, but has no effect in most nontumour cells. However, a pro-apoptotic effect has been observed in lymphocytes.
• It has no effect on embryonic development (limited research)
• Evidence on potential hormonal changes is mixed, with some evidence of
possible effects and other studies suggesting no effect, depending on the
method used and the particular hormone
• It has no effect on a wide range of physiological and biochemical parameters
or significant effects on animal behaviour unless extremely high doses are
administered (e.g., in excess of 150 mg/kg iv as an acute dose or in excess of
30 mg/kg orally daily for 90 days in monkeys)
• Effects on the immune system are unclear; there is evidence of immune
suppression at higher concentrations, but immune stimulation may occur at lower concentrations.
• There is potential for CBD to be associated with drug interactions through
inhibition of some cytochrome P450 enzymes, but it is not yet clear whether
these effects occur at physiological concentrations.


Adverse Reactions in Humans
As noted above, CBD does not produce the effects that are typically seen with
cannabinoids such as THC. It also failed to produce significant effects in a human
14 study of abuse potential discussed below. [34] Across a number of controlled and open label trials CBD of the potential therapeutic effects of CBD it is generally well."

THE CONCLUSION: 

We invite you to have a full read at the WHO document linked above and gain your own knowledge, however 800 ~ 1000mg seems to be the upper amount for consumption without problem, the WHO seems to say so anyway. 

CBD doesn't posses a high toxicology index so it's pretty unclear how much is the limit however based on the document you may have just read (well the excerpt at least) CBD is generally only going to produce good effects in the body. 

So if you suffer from any of the conditions that CBD can "allegedly" help with then we think that you should be bathing in it, drinking it, nebulising it and washing your face with it! 

Welcome to the murky world of CBD advice. Can you see now how theres a lot of room for snake oil sales people? 

We hope we've helped clear a bit of the mystery up and hopefully have put you on to a great resource in the WHO document. 

Feel free to share it with friends and family and educate those that you care about. 

 

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